Crimean-Congo Hemorrhagic Fever Virus Infection in Domestic Ruminants in Van Province, a Non-endemic Region in Turkey

Background: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease of humans that most widespread in Africa, Asia, the Middle East and Southeast Europe. The has continued to be health problem Turkey other endemic countries recent years. CCHF virus does not cause clinical animal hosts but develops an antibody response transient viraemia. aim this study evaluate status infection serologically virologically livestock Van region, non-endemic area Turkey. Methods: A total 491 whole blood serum specimens were collected from cattle, sheep goats different locations province May 2020 October 2021. To determine CCHFV-specific antibody, all sera animals tested with double-Ag ELISA-Ab kit. An RT-PCR assay was performed on leucocyte samples for virological detect presence European lineage-1 CCHFV nucleic acids viraemic animals. Result: prevalence antibodies found 36.4%. seroprevalence values detected 11.6%, 64.45% 81.63% goats, respectively. In assay, 1.22% (6/491) at time sampling.